Pokcet finding alogorithms (incomplete list)

• SplitPocket

• A web server to identify functional surfaces of protein from structure coordinates.

• LIGSITEcsc

• A web server for the automatic identification of pockets on protein surface using the Connolly...

• KVFinder

• A highly versatile and easy-to-use tool for cavity prospection and spatial characterization....

• pocketZebra

• Web-server for selection and classification of subfamily-specific binding sites by bioinformatic...

• PocketPicker

• An automated grid-based technique for the prediction of protein binding pockets that specifies...

• metaPocket

• A meta server to identify ligand binding sites on protein surface.

• fpocket

• An open source protein pocket (cavity) detection algorithm based on Voronoi tessellation.

• PLB_SAVE

• Predicts protein-ligand binding region by computing features of solid angle, volume and depth.

• CCCPP

• Computes the void parts of the proteins, i.e. cavities, channels and pockets. The present...

• SURFNET

• Generates molecular surfaces and gaps between surfaces from 3D coordinates supplied in a...

• PocketAnalyzer(PCA)

• An automated approach to diverse pocket selection. PocketAnalyzer(PCA) combines a geometric...

• CASTp

• An online tool that locates and measures pockets and voids on 3D protein structures. CASTp...

• LISE

• A web server for a novel method for predicting small molecule binding sites on proteins.

• PocketFEATURE

• Focuses on pockets using the FEATURE system for characterizing microenvironments. The method is...

• ConCavity

• A small molecule binding site prediction algorithm that integrates evolutionary sequence...

• ghecom

• A program for finding multi-scale pockets on protein surfaces using mathematical morphology.

• POCASA

• An automatic program that implements the algorithm named Roll which can predict binding sites by...

• Methods for the prediction of protein-ligand binding sites for structure-based drug design and virtual ligand screening

• Authors: Laurie, A.T., and Jackson, R.M. Abstract: Structure Based Drug Design (SBDD) is a...

• Epock

• An efficient command-line tool that calculates pocket volumes from Molecular Dynamics (MD)...

• PockDrug

• Predicts pocket druggability, efficient on both; estimated pockets guided by the ligand proximity...